Jianwen Que
Appearances
- DateMay 9, 2023Background: Eosinophilic Esophagitis (EoE) is one of the most predominant causes of chronic esophageal symptoms in children. Pathological changes of the esophageal epithelium in EoE are characterized by basal cell hyperplasia (BCH), infiltration of eosinophils and elevated levels of cytokines (e.g…
Presenter
Columbia University Irving Medical Center - DateMay 9, 2023BACKGROUND: Barrett’s Esophagus (BE) develops after reflux-mediated injury to distal esophagus and is only known precursor of esophageal adenocarcinoma (EAC), a highly deadly and increasingly prevalent cancer…
- DateMay 8, 2023The speakers in this session will provide insights into diverse molecular mechanisms of metaplasia, dysplasia and neoplasia across the esophagus, stomach, and colon…
- DateMay 20, 2024INTRODUCTION: Eosinophilic esophagitis (EoE) is an inflammatory disorder characterized by esophageal eosinophilia, basal cell hyperplasia (BCH), and epithelial barrier dysfunction promoted by inflammatory cytokines, including interleukin (IL)-13…
Presenter
Speakers
Temple University Lewis Katz School of MedicineThe Children's Hospital of PhiladelphiaColumbia University - DateMay 21, 2024BACKGROUND: The incidence of esophageal adenocarcinoma (EAC) is rapidly increasing in Western countries. Most EACs originate from Barrett’s esophagus (BE), a precancerous lesion initiated by chronic reflux of gastrointestinal contents, especially acidic bile salts (ABS)…
- DateMay 20, 2024BACKGROUND: The most common risk factor for esophageal adenocarcinoma is gastroesophageal reflux disease (GERD), a digestive disorder that affects 20% of adults in North America…