Amanda Muir

The field of EoE is undergone remarkable and dramatic changes in the last decade. With the advent of biologics, a better understanding of all current treatment options and how to pick the right option for a given patient is needed…

The field of EoE is undergone remarkable and dramatic changes in the last decade. With the advent of biologics, a better understanding of all current treatment options and how to pick the right option for a given patient is needed…

BACKGROUND: Enterochromaffin cells (ECs) are specialized gastrointestinal (GI) epithelial cells that transduce luminal forces and chemicals into release of signal molecules including serotonin (5-HT) to alter GI function including mucosal ion transport…

SOCIETY: AGA Aberrant proliferation of cell types along the GI tract is a hallmark of pathologies both benign and malignant…

BACKGROUND: Eosinophilic esophagitis (EoE) is an allergic inflammatory disorder in which chronic inflammation leads the development of fibrosis and stricture formation. Unfortunately, the mechanisms underlying fibrosis remain elusive…

BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory disorder characterized by persistent inflammation, decreased esophageal distensibility, and esophageal stricture…

SOCIETY: AGA This session will present a review of what's new in pancreatic disease along with talks on management of children with pancreatic diseases

INTRODUCTION: Although the pathobiology of eosinophilic esophagitis (EoE) remains incompletely understood, Th2 cytokines IL-4 and IL-13 are key mediators of the disease…

BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus characterized by eosinophilic inflammation as well as impaired epithelial differentiation and barrier integrity…

INTRODUCTION: Eosinophilic esophagitis (EoE) is an inflammatory disorder characterized by esophageal eosinophilia, basal cell hyperplasia (BCH), and epithelial barrier dysfunction promoted by inflammatory cytokines, including interleukin (IL)-13…

Common presenting symptoms including dysphagia, chest pain, and food impaction are thought to be mediated by inflammatory or fibrotic-associated events in the esophagus. However recent evidence supports a role for esophageal dysmotility in the histologic, endoscopic, and clinical activity in EoE…