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3390

Functional Obstruction in EGIDs: Mechanics to Molecular Mechanisms

Date
May 4, 2025
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Thumbnail for DDW 2025 - Full Program On Demand
Don't miss the opportunity to access the latest research and discoveries in the field of digestive diseases. DDW On Demand is a valuable and convenient way to enhance your knowledge and skills in digestive disease care…

Society: AGA

Common presenting symptoms including dysphagia, chest pain, and food impaction are thought to be mediated by inflammatory or fibrotic-associated events in the esophagus. However recent evidence supports a role for esophageal dysmotility in the histologic, endoscopic, and clinical activity in EoE. The major inflammatory components that drive the immunopathogenesis of EoE, mast cells and eosinophils regulate visceral motility and function in the esophagus. This session will feature speakers who will describe esophageal motor abnormalities in EoE, define techniques for assessment, manometric characteristics, and clinical implications of dysmotility in patients with EoE and discuss the mechanisms through which inflammatory cells and mediators modulate esophageal dysmotility.

Moderators

Speaker Image for Simon Hogan
Michigan Medicine
Speaker Image for Amanda Muir
The Children's Hospital of Philadelphia