Kelly Whelan

This session will feature speakers who will examine the mechanisms of inflammation and epithelial tissue remodeling during eosinophilic esophagitis (EoE). Epithelial cell and immune cell biology will be discussed…

Background: Eosinophilic Esophagitis (EoE) is one of the most predominant causes of chronic esophageal symptoms in children. Pathological changes of the esophageal epithelium in EoE are characterized by basal cell hyperplasia (BCH), infiltration of eosinophils and elevated levels of cytokines (e.g…

SOCIETY: AGA Aberrant proliferation of cell types along the GI tract is a hallmark of pathologies both benign and malignant…

INTRODUCTION: Although the pathobiology of eosinophilic esophagitis (EoE) remains incompletely understood, Th2 cytokines IL-4 and IL-13 are key mediators of the disease…

BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus characterized by eosinophilic inflammation as well as impaired epithelial differentiation and barrier integrity…

INTRODUCTION: Eosinophilic esophagitis (EoE) is an inflammatory disorder characterized by esophageal eosinophilia, basal cell hyperplasia (BCH), and epithelial barrier dysfunction promoted by inflammatory cytokines, including interleukin (IL)-13…

INTRODUCTION: Patients with the allergic disease eosinophilic esophagitis (EoE) have been shown to have a diminished risk of developing esophageal malignancy…

SOCIETY: AGA