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Inflammatory Tuning of Gut Epithelial Proliferation
Date
May 21, 2024
SOCIETY: AGA Aberrant proliferation of cell types along the GI tract is a hallmark of pathologies both benign and malignant. This session will feature speakers who will examine the mechanisms through which inflammatory cells and mediators modulate proliferation of epithelial cells in the esophagus, stomach, and intestine. Epithelial cell and immune cell biology will be discussed.
BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus characterized by eosinophilic inflammation as well as impaired epithelial differentiation and barrier integrity…
INTRODUCTION: Although the pathobiology of eosinophilic esophagitis (EoE) remains incompletely understood, Th2 cytokines IL-4 and IL-13 are key mediators of the disease…