Wael El-Rifai

BACKGROUND: Barrett’s Esophagus (BE) develops after reflux-mediated injury to distal esophagus and is only known precursor of esophageal adenocarcinoma (EAC), a highly deadly and increasingly prevalent cancer…

BACKGROUND: Gut microbiota composition and diversity have been shown to influence the effectiveness of cancer immunotherapies…

The speakers in this session will provide insights into diverse molecular mechanisms of metaplasia, dysplasia and neoplasia across the esophagus, stomach, and colon…

Countries with a high prevalence of gastric cancers have well developed programs aimed at identifying and monitoring gastric cancer precursors. However, there is limited information about the performance of such programs in the United States…

BACKGROUND: Gastric cancer (GC) is the fourth most common cause of cancer-related death worldwide. GC has a dismal 5-year survival rate of about 32%, decreasing to 5% for stage IV diagnoses. Helicobacter pylori (H. pylori) infection is the strongest risk factor for gastric carcinogenesis…

BACKGROUND In gastrointestinal cancers, Aurora kinase A (AURKA) is amplified. Stomach stem cells can be identified by SOX9 which plays a role in gastric tumorigenesis. The primary risk factor for gastric cancer is infection with _H. pylori_…

BACKGROUND: The incidence of esophageal adenocarcinoma (EAC) is rapidly increasing in Western countries. Most EACs originate from Barrett’s esophagus (BE), a precancerous lesion initiated by chronic reflux of gastrointestinal contents, especially acidic bile salts (ABS)…

BACKGROUND: The most common risk factor for esophageal adenocarcinoma is gastroesophageal reflux disease (GERD), a digestive disorder that affects 20% of adults in North America…