Oliver McDonald

BACKGROUND: Barrett’s Esophagus (BE) develops after reflux-mediated injury to distal esophagus and is only known precursor of esophageal adenocarcinoma (EAC), a highly deadly and increasingly prevalent cancer…

BACKGROUND In gastrointestinal cancers, Aurora kinase A (AURKA) is amplified. Stomach stem cells can be identified by SOX9 which plays a role in gastric tumorigenesis. The primary risk factor for gastric cancer is infection with _H. pylori_…

BACKGROUND: _Helicobacter pylori _infection is the main risk factor for gastric cancer. Fibroblast growth factor receptor 4 is a member of transmembrane tyrosine kinase receptors that are activated in cancer…

BACKGROUND: The incidence of esophageal adenocarcinoma (EAC) is rapidly increasing in Western countries. Most EACs originate from Barrett’s esophagus (BE), a precancerous lesion initiated by chronic reflux of gastrointestinal contents, especially acidic bile salts (ABS)…