Current guidelines advise esophagectomy for submucosal esophageal adenocarcinoma (T1b EAC). However, data from retrospective studies suggest that endoscopic follow-up (FU) may be a valid alternative in patients without signs of lymph node metastases (LNM) at baseline…
Focal cryoballoon ablation (FCBA) is a relatively new ablation modality for the treatment of Barrett’s esophagus (BE) related neoplasia. This prospective, European multicenter study (Euro-Coldplay, NTR NL7253) aimed to evaluate the efficacy and safety of FCBA for the treatment of limited BE…
INTRODUCTION: Colonoscopy reduces colorectal cancer mortality via the identification and removal of neoplastic polyps. In clinical trials, computer aided detection (CADe) improves polyp detection, but there is limited data of CADe implementation in routine practice…
BACKGROUND: Virtual Chromoendoscopy (VCE) has proven effective in predicting disease activity in Ulcerative Colitis (UC), although challenges persist regarding local availability and expertise…
Endoscopic myotomy (POEM) was shown equally effective as laparoscopic Heller myotomy (LHM) in patients with achalasia at two years in a multicenter randomized trial. Postprocedural reflux esophagitis and treatment with acid inhibitors were more frequent after POEM…
Aims: to develop and validate a new scale for mucosal visualization of the upper gastrointestinal tract during esophagogastroduodenoscopy (EGD), the Gastroscopy RAte of Cleanliness Evaluation (GRACE), as a quality standard tool through the application of a standardized, reliable, and validated scor…
Assessment of mucosal healing as a key denominator in the treat-to-target strategy for managing ulcerative colitis remains challenging. To address this, objective evaluation of histological disease activity holds promise…
Artificial intelligence-based polyp detection systems (CADe) have demonstrated to increase lesion detection during colonoscopy in average risk population although this seems to be mainly due to small and non-advance lesions…
Optimal management following radical endoscopic resection (R0 ER) of T1 esophageal adenocarcinoma (EAC) is still a matter of debate due to conflicting reports on the risk for lymph node metastases (LNM). In case of histological risk factors for LNM, i.e…