Current guidelines advise esophagectomy for submucosal esophageal adenocarcinoma (T1b EAC). However, data from retrospective studies suggest that endoscopic follow-up (FU) may be a valid alternative in patients without signs of lymph node metastases (LNM) at baseline…
Current guidelines advise esophagectomy for submucosal esophageal adenocarcinoma (T1b EAC). However, data from retrospective studies suggest that endoscopic follow-up (FU) may be a valid alternative in patients without signs of lymph node metastases (LNM) at baseline…
Sentinel node navigated surgery (SNNS) might offer a less invasive alternative to esophagectomy to tailor the extent of lymphadenectomy in patients with high-risk T1 esophageal adenocarcinoma (EAC)…
Focal cryoballoon ablation (FCBA) is a relatively new ablation modality for the treatment of Barrett’s esophagus (BE) related neoplasia. This prospective, European multicenter study (Euro-Coldplay, NTR NL7253) aimed to evaluate the efficacy and safety of FCBA for the treatment of limited BE…
BACKGROUND: Using EsoCheck (EC), a non-endoscopic balloon device for sampling the distal esophagus, coupled with EsoGuard (EG), a DNA based testing screening for Barrett’s esophagus (BE), we have previously reported high sensitivity and specificity for detection of BE among patients with known BE c…
Aims: to develop and validate a new scale for mucosal visualization of the upper gastrointestinal tract during esophagogastroduodenoscopy (EGD), the Gastroscopy RAte of Cleanliness Evaluation (GRACE), as a quality standard tool through the application of a standardized, reliable, and validated scor…
Endoscopic full thickness resection (eFTR) is increasingly used as a minimally invasive diagnostic and potential therapeutic approach for smaller (≤2cm) T1 colorectal cancer (CRC)…
Optimal management following radical endoscopic resection (R0 ER) of T1 esophageal adenocarcinoma (EAC) is still a matter of debate due to conflicting reports on the risk for lymph node metastases (LNM). In case of histological risk factors for LNM, i.e…
Barrett’s esophagus (BE) with early neoplasia is an indication for endoscopic treatment. Patients with non-dysplastic BE are typically enrolled in an endoscopic surveillance program to enable early detection, and treatment, of BE related neoplasia…
The neoplastic progression risk in Barrett’s Esophagus (BE) increases with increasing BE length. Therefore, some guidelines recommend that patients with ultra long-segment BE ≥10cm (ULS-BE) are referred to an expert center, however, recommendations on further management are lacking…