Current guidelines advise esophagectomy for submucosal esophageal adenocarcinoma (T1b EAC). However, data from retrospective studies suggest that endoscopic follow-up (FU) may be a valid alternative in patients without signs of lymph node metastases (LNM) at baseline…
Introduction: Shifts towards high-fat, low-fiber diets, may contribute to the rising incidence of esophageal adenocarcinoma (EAC). In mice high-fat diet promotes EAC, possibly through effects on the gut microbiome and the systemic bile acid pool…
Colonoscopy surveillance intervals are based on the predicted risk of metachronous colorectal cancer (CRC) after polyp removal. Due to the presence of co-existent findings at baseline colonoscopy, risk estimation per specific polyp subtype is difficult…
Colonoscopy surveillance intervals are based on the predicted risk of metachronous colorectal cancer (CRC) after polyp removal. Due to the presence of co-existent findings at baseline colonoscopy, risk estimation per specific polyp subtype is difficult…
Gastric cancer (GC) incidence is declining and too low in the US to recommend general population screening. However, the risk of developing GC in the US is substantially higher in ethnic minorities, potentially warranting screening in specific population subgroups. While _H…
BACKGROUND: Evidence of gastric cancer (GC) screening’s impact on GC incidence remains limited, hindering the development of health policies for screening programs. We aimed to assess the population impact of organized GC screening programs on GC incidence in Seoul, South Korea…
Colorectal cancer (CRC) screening programmes have been shown effective in reducing CRC incidence and mortality. Risk stratification offers opportunities for further optimisation of screening programmes by better balancing the harms and benefits of screening…
Colonoscopy surveillance for Lynch syndrome is burdensome and post-colonoscopy colorectal cancers (CRCs) still occur. The non-invasive faecal immunochemical test (FIT) might guide optimal colonoscopy intervals…
BACKGROUND: Accurate identification and staging of gastric intestinal metaplasia (GIM) during endoscopy is challenging, in particular in countries with a low incidence of gastric cancer (GC)…
Colonoscopy surveillance for Lynch syndrome is burdensome and post-colonoscopy colorectal cancer (CRC) still occurs. Non-invasive faecal volatile organic compounds (VOCs) might guide optimal colonoscopy intervals…
Optimal management following radical endoscopic resection (R0 ER) of T1 esophageal adenocarcinoma (EAC) is still a matter of debate due to conflicting reports on the risk for lymph node metastases (LNM). In case of histological risk factors for LNM, i.e…
The neoplastic progression risk in Barrett’s Esophagus (BE) increases with increasing BE length. Therefore, some guidelines recommend that patients with ultra long-segment BE ≥10cm (ULS-BE) are referred to an expert center, however, recommendations on further management are lacking…