Chi Chun Wong
Appearances
- DateMay 7, 2023BACKGROUND: Enterochromaffin cells (ECs) are specialized gastrointestinal (GI) epithelial cells that transduce luminal forces and chemicals into release of signal molecules including serotonin (5-HT) to alter GI function including mucosal ion transport…
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The Chinese University of Hong Kong - DateMay 7, 2023BACKGROUND AND AIMS: Peptostreptococcus stomatis (_P. stomatis_) is an enriched bacterium in colorectal cancer (CRC) patients as compared to healthy subjects in multiple cohorts. However, the potential role of _P. stomatis_ in colorectal tumorigenesis remains obscure…
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The Chinese University of Hong Kong - DateMay 7, 2023BACKGROUND AND AIMS: Peptostreptococcus stomatis (_P. stomatis_) is an enriched bacterium in colorectal cancer (CRC) patients as compared to healthy subjects in multiple cohorts. However, the potential role of _P. stomatis_ in colorectal tumorigenesis remains obscure…
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- DateMay 7, 2023Background: Nonalcoholic steatohepatitis (NASH) is a major cause of liver-related morbidity, mortality, and the leading indication for liver transplant in the US. Fibrosis is the best predictor of clinical outcomes in NASH…
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- DateMay 6, 2023BACKGROUND: Immune checkpoint blockade has revolutionized cancer treatment by harnessing the patient’s native anti-tumor T cells, but most colorectal cancers do not respond, for unclear reasons…
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- DateMay 9, 2023BACKGROUND AND AIMS: Chemoresistance is a major cause of colorectal cancer (CRC) recurrence and death. The critical role of gut microbiome in the efficacy of CRC chemotherapy remains unclear…
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The Chinese University of Hong Kong - DateMay 7, 2023_Objective_: To investigate the clinical relevance of fecal microbial dysbiosis in HCC development
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The Chinese University of Hong Kong - DateMay 8, 2023BACKGROUND: The LI-RADS (Liver Reporting and Data Systems) was created to standardize reporting of CT/MR imaging for liver masses in cirrhosis patients at risk of hepatocellular carcinoma (HCC)…
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The Chinese University of Hong Kong - DateMay 19, 2024BACKGROUND. Tumorigenesis in the right-sided and left-sided colon demonstrated distinct morphology and molecular features. However, little is known about the impact of anatomical location of colon adenoma on its interaction with the tumor microenvironment in facilitating tumorigenesis…
- DateMay 20, 2024BACKGROUND: Around 80-85% of colorectal cancer (CRC) belongs to ‘immune cold’ microsatellite stable (MSS) subtype without responsive to anti-PD-1 mAb therapy…
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The Chinese University of Hong Kong - DateMay 18, 2024BACKGROUND: The roles of probiotics in inhibiting gastric cancer (GC) and effecting _H. pylori_ infection are largely unclear. We identified _Faecalibacterium prausnitzii_ is depleted in GC. We aimed to evaluate the antitumorigenic function and molecular mechanism of _F…
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The Chinese University of Hong Kong - DateMay 20, 2024BACKGROUND: RNA N6-methyladenoine (m6A) modification plays multifaceted roles in cancer, including tumor initiation, progression and therapy resistance. Nevertheless, the role of aberrant m6A in cancer stem cells (CSCs) remains unclear…
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