232
TARGETED IN VIVO COMPETITION AMONG CO-INFECTING HELICOBACTER PYLORI STRAINS INCREASES CAGA-DEPENDENT INFLAMMATION, INJURY, AND CARCINOGENESIS WITHIN THE CONTEXT OF IRON DEFICIENCY
Date
May 18, 2024
Tracks
Related Products
H pylori and Gastric Cancer - Updates in Pathogenesis and Diagnosis
SOCIETY: AGA Mechanisms underlying H pylori related gastric pathology
IL-17 SUPPRESSES PATHOGENESIS AND STEM CELL ACTIVATION WITHIN THE CONTEXT OF CHRONIC <i>HELICOBACTER PYLORI</i> INFECTION
BACKGROUND: Perianal fistulae are highly morbid complications of Crohn’s disease (CD) with a cumulative incidence of 20-25%; despite demonstrated efficacy of infliximab treatment, estimates of complete resolution are only 20-30%. Ultimately, 20% of patients will require proctectomy…
EVALUATION OF THE SAFETY AND EFFICACY OF EFLORNITHINE (DIFLUOROMETHYLORNITHINE, DFMO) IN PATIENTS WITH GASTRIC PREMALIGNANT CONDITIONS IN THE HIGH INCIDENCE AREAS OF LATIN AMERICA
BACKGROUND. Gastric adenocarcinoma (GAC) is the third leading global cause of cancer mortality and the leading infection-associated cancer. In the U.S., GAC represents a major cancer disparity, with incidence rates 2-3X in non-white populations…
IMPLICATION OF HYPUSINATION IN HELICOBACTER PYLORI-INDUCED GASTRIC CARCINOGENESIS
INTRODUCTION: Dysregulated polyamine metabolism during _Helicobacter pylori_ infection can lead to the development of gastric cancer. The polyamine spermine is back-converted to spermidine by spermine oxidase (SMOX). We have shown that _H…