INTRODUCTION. Our previous study reported a significant increase in metachronous recurrence of early gastric cancer after endoscopic submucosal dissection due to CD44v9-positive cancer stem-like cells in _H. pylori_-infected stomach tissue (_BR. J. CANCER_ 109:379, 2013)…
_Helicobacter pylori_ is the strongest risk factor for gastric cancer; however, only a minority of infected individuals develop disease. One microbial cancer-linked locus is the _cag_ type 4 secretion system (_cag_T4SS), which translocates the oncoprotein CagA into host cells…
_Helicobacter pylori _is the strongest known risk factor for gastric cancer, and pathologic outcomes are mediated via complex interactions among _H. pylori _virulence factors, host immune responses, and the exposome…