Introduction: Shifts towards high-fat, low-fiber diets, may contribute to the rising incidence of esophageal adenocarcinoma (EAC). In mice high-fat diet promotes EAC, possibly through effects on the gut microbiome and the systemic bile acid pool…
BACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP1RAs) are associated with delayed gastric emptying, which has raised concerns regarding the risk of adverse anesthesia events (e.g., aspiration) among GLP1RA-treated patients…
Background: Bile acids comprise a major component of refluxate in GERD, the major risk factor for Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC). Bile acids are metabolized by bacteria, and bacterial composition is also impacted by exposure to bile acids…