The mammalian tissues express a huge number of circular RNAs (circRNAs) with an active role in gene regulation. circRNAs are covalently closed at the 5’ and 3’ ends, unusually stable, and are highly distributed in the cytoplasm…
The mammalian tissues express a huge number of circular RNAs (circRNAs) with an active role in gene regulation. circRNAs are covalently closed at the 5’ and 3’ ends, unusually stable, and are highly distributed in the cytoplasm…
Paneth cells reside at the bottom of the crypts in the small intestine and are crucial for maintaining homeostasis of the epithelium by engendering host protection from enteric pathogens…
Intestinal epithelial cells comprise diverse cells with specific functions, e.g., chemosensory tuft cells are important for anti-helminthic and -protozoan immunity and mucus secretion by goblet cells provides mucosal protection…
Gut barrier dysfunction occurs commonly in various pathologies, but the exact mechanism underlying the barrier disruption remains largely unknown. Mammalian genomes transcribe a vast number of noncoding RNAs (ncRNAs) with active roles in gene regulation…