Cassandra Cairns

The mammalian tissues express a huge number of circular RNAs (circRNAs) with an active role in gene regulation. circRNAs are covalently closed at the 5’ and 3’ ends, unusually stable, and are highly distributed in the cytoplasm…

Intestinal epithelial cells comprise diverse cells with specific functions, e.g., chemosensory tuft cells are important for anti-helminthic and -protozoan immunity and mucus secretion by goblet cells provides mucosal protection…

Gut barrier dysfunction occurs commonly in various pathologies, but the exact mechanism underlying the barrier disruption remains largely unknown. Mammalian genomes transcribe a vast number of noncoding RNAs (ncRNAs) with active roles in gene regulation…

Small noncoding vault RNAs (vtRNAs) are highly expressed in many eukaryotes and have been linked to different cell functions and pathologies…