The wiring of the enteric nervous system (ENS) is a dynamic process throughout development and adulthood. In the embryo, enteric neural crest derived cells expand and differentiate into the glia and neurons that form the ENS…
A hallmark symptom of inflammatory bowel disease is abnormal colon motility, largely attributed to changes in enteric nervous system (ENS) function, but studies of dysmotility are based on models of ENS-driven peristalsis in distal colon regions…