USING ORGANIODS TO MODEL THE COMPLEXITY OF HUMAN INTESTINAL BIOLOGY AND DISEASES

BACKGROUND: Recent studies suggest links between _Clostridioides difficile_ infection (CDI) and liver disorders, with non-alcoholic fatty liver disease (NAFLD) increasing CDI risk and CDI exacerbating the progression and prognosis of liver cirrhosis. Moreover, gut dysbiosis, often leading to _C…

MECHANOGATED ION CHANNEL PIEZO2 TETHERS TO THE ACTOMYOSIN CYTOSKELETON IN INTESTINAL EPITHELIAL MECHANORECEPTORS

SOCIETY: AGA Mechanistic studies in GI diseases, including eosinophilic esophagitis, obesity, inflammatory bowel disease, and intestinal pseudo-obstruction, and therapeutic outcomes such as FMT will be explored…

SOCIETY: AGA Discover innovative approaches to study gastrointestinal biology and pathophysiology using organoids and engineered organ systems…