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GLUTEN DEPENDENT ACTIVATION OF CD4+ T CELLS BY MHC CLASS II EXPRESSING INTESTINAL EPITHELIAL CELLS
BACKGROUND AND AIM: Intestinal epithelial cells (IECs) are emerging as potential regulators of CD4+ T cell responses through MHC class II expression. However, their role as antigen-presenting cells and in the activation of gluten-reactive CD4+ T cells has never been proven…
A PROSPECTIVE, MULTI-INSTITUTIONAL STUDY REVEALS THE COMBINATION OF RNA ANALYSIS WITH DNA-BASED NEXT-GENERATION SEQUENCING (NGS) IMPROVES THE PREOPERATIVE CLASSIFICATION OF PANCREATIC CYSTS AND IDENTIFICATION OF ADVANCED NEOPLASIA
BACKGROUND: As outlined by the Kyoto guidelines, targeted DNA-based NGS of pancreatic cyst fluid (PCF) is an important adjunct to the evaluation of pancreatic cyst patients…
