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SOCIETY: AGA The intestine is the largest immune organ and is also heavily innervated by intrinsic and extrinsic neurons. Emerging data show multiple modes of interaction between cells of the nervous system (neurons and glia) and immune cells that impact both intestinal health and disease processes. This session will provide attendees with a current understanding of mechanisms by which the nervous system tunes intestinal immunity in health and disease, and how immune cells affect neural-controlled gut functions. The session will include three 25 min presentations by experts in the field followed by three 15 min presentations selected from submitted abstracts.