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Sp393
GLP-1S IN THE TREATMENT OF OBESITY AND DIABETES
Date
May 7, 2023
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Enteroendocrine cells play a major role in sensing the luminal contents of the gut and communicating with other organs such as the pancreas, liver and brain. The gut-brain connection is essential in the regulation of food intake. These interaction is neuro-hormonal and mediated by incretin hormones such as GLP-1. Recently, GLP-1 receptor analogs were FDA-approved for obesity and diabetes.
Background: Transoral outlet reduction endoscopy (TORe) has been shown to be effective in managing weight regain after Roux-en-Y gastric bypass (RYGB), as has the glucagon-like peptide-1 agonist, liraglutide. However, the effect of adjunctive liraglutide after TORe has yet to be assessed…
Enteroendocrine cells play a major role in sensing the luminal contents of the gut and communicating with other organs such as the pancreas, liver and brain. The gut-brain connection is essential in the regulation of food intake…