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AGA Enteroendocrine Cells and Incretins: From Basic Science to Blockbuster Drugs
Date
May 7, 2023
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Society: AGA
Enteroendocrine cells play a major role in sensing the luminal contents of the gut and communicating with other organs such as the pancreas, liver and brain. The gut-brain connection is essential in the regulation of food intake. These interaction is neuro-hormonal and mediated by incretin hormones such as GLP-1. Recently, GLP-1 receptor analogs were FDA-approved for obesity and diabetes.
Enteroendocrine cells play a major role in sensing the luminal contents of the gut and communicating with other organs such as the pancreas, liver and brain. The gut-brain connection is essential in the regulation of food intake. These interaction is neuro-hormonal and mediated by incretin hormones such as GLP-1. Recently, GLP-1 receptor analogs were FDA-approved for obesity and diabetes.
Moderators
Mayo Foundation for Medical Education and Research
University of Pennsylvania
General
Tracks
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