Unveiling the Intricate Link between Parkinson's Disease and the Gastrointestinal Tract

SOCIETY: AGA Gastrointestinal (GI) involvement is frequently observed in Parkinson's Disease (PD), with GI symptoms, including constipation, being highly prevalent in prodromal PD. Mounting evidence points to the growing importance of a-synucleinopathies in the enteric and central nervous systems in the pathophysiology of PD. This expert panel will delve into the early accumulation of a-synucleins, its implications in GI dysmotility, and the broader understanding of PD's impact on the GI system. The discussion will encompass the various manifestations of PD in the GI tract, focusing on constipation. Attendees will gain insights into the role of motility testing in evaluating GI symptoms in PD and receive a comprehensive overview of management approaches and novel treatment strategies. This session is timely since the NIH recently held a state-of-the-science conference focused on Parkinson?s disease and the gut.

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