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BRAF POSITIVE INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS (IPMN) HAVE VARIABLE PRESENTING SYMPTOMS, MORPHOLOGIC FEATURES, CYST FLUID ANALYTE, AND SOMATIC MUTATION PROFILES, WHEN COMPARED WITH BRAF NEGATIVE: A MULTICENTER PROSPECTIVE COHORT STUDY
Clinical presentation, imaging, and endoscopic ultrasound (EUS) findings, as well as fluid analysis possess prognostic features for intraductal papillary mucinous neoplasms (IPMN); however, classification of IPMN-risk remains challenging1,2…
COSTS ASSOCIATED WITH PANCREATIC CYST SURVEILLANCE DECREASED AFTER RISK-STRATIFICATION WITH NEXT-GENERATION SEQUENCING
Incidental detection of pancreatic cysts (PCs) is increasing and identifying high-risk cysts is of critical importance. Prior studies suggest significant cost associated with PC surveillance, which is more pronounced with over-management…
THE CLINICAL IMPACT AND COST-EFFECTIVENESS OF DIAGNOSTIC MODALITIES FOR INDETERMINATE BILIARY STRICTURES, INCLUDING NEXT-GENERATION SEQUENCING AND ARTIFICIAL INTELLIGENCE: A MICROSIMULATION ANALYSIS
Indeterminate biliary strictures persist as a diagnostic challenge, particularly due to the concern of delayed diagnosis of malignancy…
A PROSPECTIVE, MULTI-INSTITUTIONAL STUDY REVEALS THE COMBINATION OF RNA ANALYSIS WITH DNA-BASED NEXT-GENERATION SEQUENCING (NGS) IMPROVES THE PREOPERATIVE CLASSIFICATION OF PANCREATIC CYSTS AND IDENTIFICATION OF ADVANCED NEOPLASIA
BACKGROUND: As outlined by the Kyoto guidelines, targeted DNA-based NGS of pancreatic cyst fluid (PCF) is an important adjunct to the evaluation of pancreatic cyst patients…
