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Sp263
PANEL DISCUSSION
Date
May 18, 2024
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SOCIETY: AGA Environmental factors influence the pathogenesis of IBD. Experimental evidence has been critical in providing mechanistic insights into how environmental factors affect gut inflammation…
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) maintains mononuclear phagocytes (MNP) and supports intestinal immune homeostasis. Anti-GM-CSF autoantibodies (aGMAbs) are found in approx. 25% of all Crohn’s disease (CD) patients…
Anti-granulocyte/macrophage-colony stimulating factor autoantibody (GM-CSF AuAB) has been identified before the onset of Crohn’s Disease (CD) and is associated with an increase in complicated disease. However, its connection to the gut microbiome, a key factor in CD progression, remains unclear…