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FAECAL MICROBIOME AS TARGETED NON-INVASIVE BIOMARKERS FOR INFLAMMATORY BOWEL DISEASE: A CROSS-POPULATION METAGENOMIC ANALYSIS IN SIX COHORTS
BACKGROUND Emerging data support the importance of gut microbiome alterations in the pathogenesis of inflammatory bowel disease (IBD) but their role as non-invasive biomarkers for IBD has not been unexplored…
METAGENOMIC ANALYSIS OF INTRA-HOUSEHOLD TRANSMISSION PATTERNS OF THE GUT MICROBIOME IN CROHN'S DISEASE ACROSS POPULATIONS
BACKGROUND The gut microbiome play an important role in Crohn’s disease (CD) pathogenesis. However, the extent to which interpersonal relations shape individual genetic makeup of the microbiome and its transmission in CD patients and their household members remains unknown…
EXPOSURE TO AN INFLAMMATORY PRENATAL ENVIRONMENT AND THE RISK OF INFLAMMATORY BOWEL DISEASE IN THE OFFSPRING: A POPULATION-BASED COHORT STUDY
The strongest independent risk factor for developing inflammatory bowel disease (IBD) is a family history with IBD. The early life, including the intra-uterine period, is critical for immune system maturation and therefore, exposures during early life can influence IBD risk…
THE IMPACT OF FOOD ADDITIVE INTAKE AND ALTERED GUT MICROBIOME ON PERINATAL HEALTH: DATA FROM 3 REGIONS IN CHINA FROM THE MOMMY COHORT
KEYWORDS: food additives, maternal gut microbiome, gestational diabetes mellitus, large for gestational age
