Error loading player: No playable sources found

4215

New Knowledge and Pragmatic Guidance from Existing IBD Research: A Cochrane Symposia Demonstrating the Pitfalls and Promise of Network Meta-analyses to Inform Clinical Practice

Date
May 20, 2024

SOCIETY: AGA Clinical guidelines increasingly rely on technical reviews of evidence and these in turn are becoming increasingly complex in methods. This offers great promise to truly achieve evidence based clinical guidelines. Network Meta-analysis allows studies to be compared not just directly through pairwise analysis, but indirectly accross the network enhancing the precision and conssitency of the evidence and the resulting 'ranking' can appear to offer great promise to guiding clinical decision making. In this session, we will consdier three clinical scenarios of inducing and maintaing remission in Crohn's disease, Ulcerative Colitis and Fistulating disease. We will then exemplify the promise of this form of analysis when completed correctly and including GRADE analysis of the network with the presentation of novel graphical summaries. We will also detail the pitfalls of poor methodology and intepretation.We will use the exemplar of the update to the UK BSG guidelines to demonstrate the impact such findings can have of clinical practice guidelines.

Moderators

Speaker Image for Morris Gordon
University of Central Lancashire, UK
Speaker Image for Paul Moayyedi
McMaster University

Related Products

Thumbnail for Uncontrolled Therapeutic Observations in IBD
Uncontrolled Therapeutic Observations in IBD
SOCIETY: AGA In this session, several clinically relevant presentations will put the attendee at the cutting edge of research and clinical care, with regard to stem cells for perinal fistulas, biologic de-escalation, subcutaneous biologics, and use of small molecules in microscopic colitis
Thumbnail for IMIBD Late Breakers and Innovations in IBD
IMIBD Late Breakers and Innovations in IBD
SOCIETY: AGA By popular demand, this new session highlights the best late-breakers submitted to the IBD section and well as innovations in technology and new paradigms of care in IBD
Thumbnail for IBD Controlled Trials II
IBD Controlled Trials II
SOCIETY: AGA This session is the second session of the ever-popular and clinically impactful clinical trials sessions in IBD. Insights into novel agents including obefazimod, VTX002. MH002, risankizumab, and mirikizumab will be presented…
Thumbnail for Role of the Environment in IBD
Role of the Environment in IBD
SOCIETY: AGA As our scientific tools improve, so does our ability to link the environment with different aspects of IBD…