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Microbes, Molecules, and Metabolites: Methodical Muli-omics to Illuminate Mechanisms
Date
May 20, 2024
SOCIETY: AGA There can be no doubt that gut microbial content is a major determinant of human health and disease. However, it is easier to generate large amounts of microbial, host, and metabolic information than it is to perform cogent analyses. Here we review how to choose multi-omics technology, and models of resources to analyze resulting data. A major goal is to discuss inter-technology (horizontal) integration.
The role of nutrition and the microbiome is evident in IBD and functional bowel disorders. The microbiome can affect the way nutrients are metabolized in bioactive components. It is of important to understand the molecular sensors of such metabolized components…
SOCIETY: AGA This session will focus on the current debates about utility of small intestinal microbiome, probiotics and microbiome testing. The first debate will focus on "The Microbiome Conundrum: Unraveling the Influence of Small Intestinal Microbes on GI Symptoms - Debating Our Path Ahead"…
This session was jointly developed by AGA and representatives from the Division of Gastroenterology at the FDA Center for Drug Evaluation and Research…