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Sp877
MICORFLUIDICS TO MODEL GASTROINTESTINAL AND LIVER DISEASES
BACKGROUND The gastrointestinal tract (GI) has a sense of _gut touch_ by which low threshold mechanical inputs activate mechanoreceptors similar to Merkel cells that mediate skin touch…
BACKGROUND: Intrinsic primary afferent neurons (IPANs) of the gastrointestinal (GI) tract respond to luminal content including pressure to initiate motor reflexes. Advillin is a marker of mouse IPANs and Avil-CreERT2 mice can drive the expression of optogenetic ion channels…
BACKGROUND: Muscularis macrophages (MMs) reside in the gut muscularis propria. A population of MMs share a phenotype with microglia and produce a large amount of Complement component 1qA (C1qa)…