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INTRODUCTION: Pancreatic neuroendocrine tumors (PNETs) are a slow-growing, heterogeneous group of neoplasms arising from endocrine tissues of the pancreas. PNETs exhibit a low overall mutational burden, but the genes most commonly mutated are involved in epigenetic regulation…
Right posterior bile duct injury with disconnected duct syndrome creates diagnostic challenges for many endoscopists and radiologists. The diagnosis and treatment are often delayed…
BACKGROUND: DNA Methyltransferase inhibitors (DNMTi) have been found to increase the immunogenicity of cancer cells, reshaping the immune tumor microenvironment while directly reprogramming immune cells…