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Sp804
GASTRIC PREMALIGNANT LESIONS: KEY PATHOLOGICAL CONCEPTS FOR OPTIMIZING CLINICAL MANAGMENT
INTRODUCTION: Dysregulated polyamine metabolism during _Helicobacter pylori_ infection can lead to the development of gastric cancer. The polyamine spermine is back-converted to spermidine by spermine oxidase (SMOX). We have shown that _H…
INTRODUCTION. Our previous study reported a significant increase in metachronous recurrence of early gastric cancer after endoscopic submucosal dissection due to CD44v9-positive cancer stem-like cells in _H. pylori_-infected stomach tissue (_BR. J. CANCER_ 109:379, 2013)…
Gastric cancer is the 4th leading cause of cancer deaths worldwide. _Helicobacter pylori _infection is the primary risk factor for gastric cancer. In the United States, gastric cancer rates have been declining for several decades, likely due to reduced _H. pylori _infection rates…
BACKGROUND. Gastric adenocarcinoma (GAC) is the third leading global cause of cancer mortality and the leading infection-associated cancer. In the U.S., GAC represents a major cancer disparity, with incidence rates 2-3X in non-white populations…