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Sp1237
FUNCTIONAL DYSPHAGIA - FRAMING THE PROBLEM
Date
May 9, 2023
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As many as 30-50% of the patients referred to the tertiary care center with dysphagia symptoms have normal endoscopy, barium esophagram, and high-resolution manometry and are classified as functional dysphagia.The reason for their symptoms remains unknown and management is challenging. The goal of this symposium is to showcase updates in our understanding of the physiology of esophageal peristalsis and lower esophageal sphincter function in patients with functional dysphagia.
Discerning whether laryngeal symptoms are related to reflux (laryngopharyngeal reflux; LPR) is a challenge. Consequently, patients see numerous specialists, undergo multiple diagnostic tests and empirically trial proton pump inhibitors (PPIs), often with inconsistent response…
Switching from originator to biosimilar infliximab (IFX) is effective and safe. However, data on multiple switching are scarce. The Edinburgh IBD unit has undertaken three switch programmes: (1) Remicade to CT-P13 (2016), (2) CT-P13 to SB2 (2020), and (3) SB2 to CT-P13 (2021)…
Perturbations in the gut mucosal immune response contributes to IBD. Non-immune cell popopulations including epithelial and stromal cells also play an important role in intestinal inflammation…