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TAIWAN CANCER MOONSHOT PROJECT INTERIM REPORT: DECIPHERING DIVERGENT PATHS THROUGH IN-DEPTH COMPARATIVE MULTIOMIC ANALYSIS OF H. PYLORI-ASSOCIATED AND INDEPENDENT GASTRIC CANCER SIGNATURES
Gastric cancer, ranking as the fifth most prevalent cancer globally, involves complex etiologies, including but not limited to H. pylori infection. This interim report is part of a comprehensive multi-omic analysis from the Taiwan Cancer Moonshot Project on Gastric Cancer…
COMPARISON OF EMPIRICAL THERAPY VERSUS SUSCEPTIBILITY TESTING-GUIDED THERAPY FOR REFRACTORY HELICOBACTER PYLORI INFECTION: A MULTICENTER, OPEN-LABEL, RANDOMIZED CONTROLLED, NON-INFERIORY TRIAL
BACKGROUND AND AIMS: There is limited evidence to support whether optimized empirical therapy can be an alternative to susceptibility testing guided therapy for patients with refractory _Helicobacter pylori_ (_H. pylori_) infection defined as failure after two or more eradication attempts…
GENOTYPIC RESISTANCE GUIDED THERAPY VERSUS SUSCEPTIBILITY TESTING GUIDED THERAPY IN THE FIRST-LINE AND THIRD-LINE TREATMENT OF HELICOBACTER PYLORI INFECTION-TWO MULTICENTER RANDOMIZED CONTROLLED TRIALS
INTRODUCTION. Our previous study reported a significant increase in metachronous recurrence of early gastric cancer after endoscopic submucosal dissection due to CD44v9-positive cancer stem-like cells in _H. pylori_-infected stomach tissue (_BR. J. CANCER_ 109:379, 2013)…
