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INTEGRATED MULTIOMICS MARKERS HIGHLIGHT DISTINCT MICROBIAL PATHWAYS LINKED TO ICI EFFICACY AND ADVERSE EVENTS
BACKGROUND: Immune activation by immune checkpoint inhibitors (ICI) has shown promise in the treatment of diverse cancer types at the cost of different immune-related adverse events (irAEs)…
EFFICACY AND SAFETY OF DARVADSTROCEL TREATMENT IN PATIENTS WITH COMPLEX PERIANAL FISTULAS AND CROHN’S DISEASE: RESULTS FROM THE GLOBAL ADMIRE-CD II PHASE 3 STUDY
BACKGROUND: Complex perianal fistulas are a serious complication in patients with Crohn’s disease (CD)…
FECAL URGENCY IN QUIESCENT IBD IS ASSOCIATED WITH POOR QUALITY OF LIFE: A CROSS-SECTIONAL STUDY OF SPARC IBD COHORT
BACKGROUND: Fecal urgency (FU) is common in patients with active inflammatory bowel disease (IBD) and is associated with reduced well-being and poor quality of life (QOL)…
