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Sp1274
ADDING ON SECOND-LINE THERAPY TO HELP CHANGE THE COURSE OF TREATMENT IN PBC
INTRODUCTION: Elevated levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are associated with risk of poor clinical outcomes, including hepatic decompensation, liver transplant, or death, in patients (pts) with primary biliary cholangitis (PBC)…
The pancreas is composed of the epithelial and mesenchymal cells. Interaction between the two lineages guides proper formation of the pancreas and modulates progression of pancreatic diseases such as cancer…
Colorectal cancer (CRC) shows a dramatic drop in the five-year survival rate from 90% for localized tumors to 14% for metastatic CRC (mCRC). Our lab has identified LIN28B, an RNA-binding protein overexpressed in 30% of CRCs, as an oncogene that promotes CRC metastasis…
BACKGROUND: Siewert's topographic classification (SW) has been used for treatment plan of esophagogastric junction adenocarcinomas (EGJA). But recently, molecular classifications categorized EGJA with similar characteristics and prognosis…