Ying Ran

AIMS: The mechanism of gut microbiota involved in the etiopathogenesis of primary cholangitis (PBC) remains unclear. Here, we investigated the role of gut microbiota in liver immune response in PBC…

BACKGROUND: Approximately 40% of primary biliary cholangitis (PBC) patients exhibit poor response to ursodeoxycholic acid (UDCA) and prognosis, referred to as refractory PBC. There is an urgent need to explore new treatment approaches for this patient population…

Background and Objective: Biliary senescence in primary biliary cholangitis (PBC) patients is positively correlated with disease severity, prognosis, and poor UDCA response…