Wenjie Ma

BACKGROUND AND AIMS: Chemoresistance is a major cause of colorectal cancer (CRC) recurrence and death. The critical role of gut microbiome in the efficacy of CRC chemotherapy remains unclear…

BACKGROUND: Primary bile acids (PBA) and their gut microbial metabolites (secondary BA [SBA]) modulate immune function and can contribute to intestinal inflammation and tumorigenesis. Diet alters the production and metabolism of BAs…

BACKGROUND: We derived a polygenic risk score (PRS) for diverticulitis based on known susceptibility loci for diverticular disease and investigated its joint association with body mass index (BMI), a risk factor for diverticulitis…

BACKGROUND: The detrimental impact of diverticulitis on quality of life and health care expenditures, particularly among those with recurrent episodes is substantial…