BACKGROUND: Eosinophil infiltration is a hallmark of eosinophilic esophagitis (EoE). Histologic assessment of esophageal biopsies is required for diagnosis and evaluation of treatment effect. Current diagnostic criteria are based mainly upon a peak eosinophil count (PEC) ≥15…
BACKGROUND: The primary objective of the VIVID-1 trial (NCT03926130) was to demonstrate efficacy and safety of mirikizumab (miri), a p19-directed anti-IL-23 antibody, compared to placebo (PBO) in patients (pts) with moderate-to-severe Crohn’s disease…
BACKGROUND: Acute upper gastrointestinal bleeding(AUGIB) is a common emergency, with 10% linked to varices1, requiring swift evaluation. METHODS: Prospective multi-center study (3 May–2 July 2022) of adults (>16) with AUGIB in 152 UK hospitals…