Vikram Joshi

The wiring of the enteric nervous system (ENS) is a dynamic process throughout development and adulthood. In the embryo, enteric neural crest derived cells expand and differentiate into the glia and neurons that form the ENS…

Paneth cells reside at the bottom of the crypts in the small intestine and are crucial for maintaining homeostasis of the epithelium by engendering host protection from enteric pathogens…

BACKGROUND: Muscularis macrophages (MMs) reside in the gut muscularis propria. A population of MMs share a phenotype with microglia and produce a large amount of Complement component 1qA (C1qa)…

BACKGROUND: Gastrointestinal (GI) motility disorders, such as chronic constipation, dysphagia, and fecal impaction, are more common in the elderly. In the vascular system, increased tissue stiffness with age is associated with a decline in contractile function of smooth muscle cells (SMCs)…

BACKGROUND The gastrointestinal tract (GI) has a sense of _gut touch_ by which low threshold mechanical inputs activate mechanoreceptors similar to Merkel cells that mediate skin touch…

C1QA MUSCULARIS MACROPHAGES: A DYNAMIC PLAYER IN THE REGULATION OF SYNAPTIC FUNCTION AND EXPRESSION