Phosphatase and tensin homolog (PTEN) is a lipid phosphatase, while its protein phosphatase activity is being suggested. Since the classical role of PTEN as a tumor suppressor is unclear in the gut, we hypothesize PTEN’s alternative function in regulating gut homeostasis…
BACKGROUND: Cigarette smoke is a major cancer risk factor, however, mechanisms governing this interaction are still unclear. Gut microbiome, which has emerged as a major determinant of cancer growth, is known to be altered by cigarette smoke…