Sinju Sundaresan

Appearances

INHIBITION OF PYRUVATE DEHYDROGENASE KINASE 4 ENHANCES STEMNESS OF GERIATRIC INTESTINAL STEM CELLS BY INCREASING MITOCHONDRIAL OXYGEN CONSUMPTION RATE AND ATP PRODUCTION
Date
May 6, 2023
Paneth cells reside at the bottom of the crypts in the small intestine and are crucial for maintaining homeostasis of the epithelium by engendering host protection from enteric pathogens…
Speakers
Aasem Awwad
Nerise Eddy
Garrett Weber
Syed Ahmed
Robert Murphy
Presenter
Sinju Sundaresan
MITOCHONDRIAL OXIDATION OF THE CARBOHYDRATE FUEL ROBUSTLY ENHANCES STEMNESS OF OLDER AND GERIATRIC HUMAN AND MOUSE INTESTINAL STEM CELLS VIA REPROGRAMMING CELLULAR METABOLIC PREFERENCE
Date
May 21, 2024
BACKGROUND: Age induced decline in stemness of Intestinal Stem Cells (ISCs) was reported to be associated with a metabolic shift from mitochondrial oxidation to anaerobic utilization of pyruvate…
Speakers
Aasem Awwad
Garrett Weber
Nerise Eddy
Syed Ahmed
Robert Murphy
Presenter
Sinju Sundaresan