Silvio Danese

INTRODUCTION: Ileal pouch-anal anastomosis (IPAA) is the surgical procedure of choice in selected patients affected by inflammatory bowel disease (IBD). Since its inception in 1978, IPAA has undergone significant improvements mainly secondary to the changing in of surgical approaches…

The intrinsic connection between inflammation and tumor promotion is well characterized and is a key pathogenic event in patients with colorectal cancer (CRC)…