Scott Magness

BACKGROUND: RNA-binding motif protein 47 (RBM47) is a component of the APOBEC-1 dependent C-to-U RNA editosome required for RNA editing. However, the range of targets and functions of RBM47 in intestine is unknown…

Phosphatase and tensin homolog (PTEN) is a lipid phosphatase, while its protein phosphatase activity is being suggested. Since the classical role of PTEN as a tumor suppressor is unclear in the gut, we hypothesize PTEN’s alternative function in regulating gut homeostasis…

Paneth cells reside at the bottom of the crypts in the small intestine and are crucial for maintaining homeostasis of the epithelium by engendering host protection from enteric pathogens…