Rodger Liddle

SOCIETY: AGA Showcasing recent data from leading groups, this session will overview the roles of the mechanosensory ion channel PIEZO2 in the control of gastrointestinal motility, nociception, and hypersensitivity associated with inflammatory and functional gastrointestinal disorders and the cell t…

Piezo1, the pancreas' predominant mechano-gated ion channel, is highly expressed in pancreatic acinar cells. Despite specific advances in understanding the pathological effects of Piezo1 in pancreatitis and fibrosis, the physiological function of Piezo1 in the exocrine pancreas is unknown…