Richard Waldron

BACKGROUND: Pancreatic cancer (PC) features highly proliferative cancer cells and a dense stroma modulating tumor growth. Due to the invasive behavior of PC and the lack of effective treatments, there is a pressing need to develop therapies targeted at tumorigenic events to slow down PC progression…

BACKGROUND: Obesity and type-2 diabetes mellitus (T2DM) are substantial risk factors for pancreatic ductal adenocarcinoma (PDAC). Both obesity and T2DM are often linked to aberrant insulin processing in β cells and altered liver lipid metabolism…

BACKGROUND: Pancreatic ductal adenocarcinoma (PC) is a deadly cancer with a rapidly rising incidence and a low 5-year relative survival rate…