Ren Mao

Background: Mesenteric fat wrapping around the intestinal wall, so called ‘creeping fat’ (CF), is spatially linked with stricture formation in Crohn’s disease (CD)…

BACKGROUND: Inflammatory bowel disease (IBD)-associated intestinal fibrosis is a significant clinical problem. Excessive accumulation of extracellular matrix (ECM) derived from intestinal myofibroblasts (HIMF) is a hallmark of intestinal strictures…

Backgrounds: Creeping fat, a hallmark of Crohn's disease (CD), is intimately associated with intestinal fibrosis, and the formation of strictures. Histology shows that extracellular matrix (ECM) remodeling exists in the area of creeping fat…