R. Alexander Richter

The molecular circadian clock helps optimize host physiology to the environment by influencing the timing and coordination of metabolic processes. Host-microbe interactions also play an important role in determining metabolic responses to environmental challenges…

The molecular circadian clock helps optimize host physiology to the environment by influencing the timing and coordination of metabolic processes. Host-microbe interactions also play an important role in determining metabolic responses to environmental challenges…

BACKGROUND: There are few interventions that, when introduced at an advanced age in mammals, are known to improve healthspan. Caloric restriction and time-restricted feeding (TRF) improve healthspan, with up to 35% extension in lifespan when used with circadian alignment…

BACKGROUND: Obstructive sleep apnea (OSA) independently worsens atherosclerosis. Yet, the mechanisms through which OSA or its characteristic components, intermittent hypoxia and hypercapnia (IHC), increase atherosclerosis risk remain unclear…