Peter Strege

Phosphatase and tensin homolog (PTEN) is a lipid phosphatase, while its protein phosphatase activity is being suggested. Since the classical role of PTEN as a tumor suppressor is unclear in the gut, we hypothesize PTEN’s alternative function in regulating gut homeostasis…

BACKGROUND The gastrointestinal tract (GI) has a sense of _gut touch_ by which low threshold mechanical inputs activate mechanoreceptors similar to Merkel cells that mediate skin touch…