Germline genetic testing is recommended for younger patients with idiopathic pancreatitis, but there is no consensus recommendation for those over age 35. We aimed to analyze the results of genetic testing for pancreatic genetic mutations using a large dataset including all ages…
_BACKGROUND AND AIMS: _Preclinical data shows mTOR pathway upregulation in Familial Adenomatous Polyposis (FAP). Inhibition of this pathway by rapalogues, like rapamycin, suggests promising results, but poor drug bioavailability and toxicity limited effective use of these drugs in FAP trials…