Paul Moayyedi

The Cochrane Gut group supports the production of high quality and methodologically rigorous reviews for a portfolio that includes upper GI, IBD and functional bowel disease topics in adults and children…

This session presents the best submitted clinical abstracts as determined by their specific council sections…

Aconitate decarboxylase 1 (ACOD1; also known as IRG-1) is the ubiquitous source of the metabolite itaconate, which dampens inflammasome activation by preventing HIF1α production of IL-1β and prevents TNF production through NRF2 activation…

This session will feature the editors-in-chief of three leading medical journals, including Nature Medicine, Annals of Internal Medicine and Gastroenterology…

Handout [https://ddw.digitellinc…

BACKGROUND The gut microbiome is central to Crohn’s disease (CD) pathogenesis but the relative contribution of different environmental factors to disease compositional variation is unknown…

INTRODUCTION: We aimed to investigate the relationship between consumption of ultra-processed foods (UPFs) and: 1) active symptomatic disease and 2) intestinal inflammation in a cohort of adults living with inflammatory bowel disease (IBD)…

INTRODUCTION: We aimed to investigate the relationship between consumption of ultra-processed foods (UPFs) and: 1) active symptomatic disease and 2) intestinal inflammation in a cohort of adults living with inflammatory bowel disease (IBD)…

INTRODUCTION: We aimed to investigate the relationship between consumption of ultra-processed foods (UPFs) and: 1) active symptomatic disease and 2) intestinal inflammation in a cohort of adults living with inflammatory bowel disease (IBD)…

BACKGROUND: Irritable bowel syndrome (IBS) is a common disorder with complex pathophysiological mechanisms. Prior studies suggest that 25-50% of patients with diarrhea-predominant IBS (IBS-D) have evidence of bile acid (BA) diarrhea (BAD)…

SOCIETY: AGA This session will feature the editors-in-chief of leading medical journals, including Annals of Internal Medicine and Gastroenterology…

SOCIETY: AGA Clinical guidelines increasingly rely on technical reviews of evidence and these in turn are becoming increasingly complex in methods. This offers great promise to truly achieve evidence based clinical guidelines…

INTRODUCTION: Proton pump inhibitors (PPIs) have been associated with an increased risk of cerebrovascular events, cognitive decline, and dementia in observational studies. These associations may be due to residual confounding…

BACKGROUND: The Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects (IMAGINE) Strategy for Patient Oriented Research (SPOR) Chronic Disease Network is conducting a five-year multicenter prospective observational cohort study, Mind And Gut Interactions Cohort (…

Although the cause of Crohn’s disease (CD) is unknown, recent studies have identified a number of biomarkers associated with the risk of developing CD in healthy at-risk individuals…

Incidence of Crohn's disease(CD) is increasing worldwide. Previous studies suggest that exposure to air pollutants may contribute to the risk of CD…

The incidence of inflammatory bowel disease (IBD) is increasing globally. Epidemiological studies suggest an association between consumption of ultra-processed foods (UPFs) and IBD risk…

Clinical guidelines increasingly rely on technical reviews of evidence using a range of methods. These are often very similar and yet guidelines in North America, Canada, Europe and the rest of the globe can vary greatly…